Passive immunization, special protection for vulnerable groups

Elder Vaccine
(IO/Pramita Hendra)

Jakarta, IO – Vulnerable groups have a higher risk of Covid-19 infection – and they also encounter a greater risk of severity of the disease when they fall victim to it as well. Prof. Dr. dr. Iris Rengganis, Sp.PD, K-AI, FINASIM, General Chairwoman of the Indonesian Allergy and Immunology Association’s Central Management (Perhimpunan Alergi Imunologi Indonesia – “Peralmuni”), declares that the effectiveness of Covid-19 vaccine is better and more stable among a hospitalized healthy population. On the contrary, the vaccine’s effectiveness for vulnerable groups is markedly lower in general than that of the healthy population. 

According to studies, the effectiveness of the vaccine among a vulnerable population after vaccination is lower than 70%. Even after having been given 3 vaccine injections, the effectiveness for this group is far below that of the healthy population: they are three times more likely to need hospitalization, three times more likely to require intensive care in the ICU, and double having the likelihood of dying from the disease. 

Vulnerable groups have a greater risk of remaining infected with the Covid-19 virus for a prolonged duration. One of the causes for this is that the virus’ replication remains continuous for a longer period in their bodies. “Strict implementation of health protocols and booster vaccination are the two primary guards you can count on against Covid-19 infection. However, vulnerable groups need other modes or options because of their weakened condition, such as passive immunization with monoclonal antibodies,” Prof. Iris declared in the “Importance of Special Protective Measures for Vulnerable Groups during the Pandemic Era” webinar held in Jakarta, Thursday (24/11/2022).